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Jack Sisson's TBI Blog

A hug is duct tape for the soul.

In CNS Spectrums, Volume 10 (2), February 2005, authors Dan J. Stein's and Frederick G. Moeller's article, "The Man Who Turned Bad," presents a case study of a 35-year-old security guard.
William worked night shifts at a mall. One evening he was surrounded by a gang of young men seeking trouble. Before he had a chance to react, he was hit several times on the head with a baseball bat and fell unconscious. There was no evidence of a skull fracture or of hemorrhage upon viewing of brain imaging, and he was discharged the next day.

Over the next several weeks, however, it became apparent that William was not his old self. He was irritable and repeatedly got into fights with his family and co-workers.

Clinical studies of traumatic brain injury (TBI) have contributed greatly to our understanding of the cognitive-affective neuroscience of emotional regulation and its pathology, including impulsive-aggression. Imaging studies have shed light on the relevant neurocircuitry and the underlying molecular mechanisms are gradually being delineated.

Such work raises conceptual questions about the extent to which moral and evil behavior are explicable in terms of psychobiology. In TBI, perhaps the best evidence for decreasing agitation and aggression lies with the blockers. A recent systematic review of TBI also noted weak evidence that antidepressants (particularly SSRIs) and anticonvulsants are effective for these symptoms, particularly in the context of a mood disorder.

The above information was taken from PsycINFO Database Record (c) 2005 APA, all rights reserved. It should not be too difficult to find the entire article if you wish to read it.

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